Home/Technical Glossary/Glovebox Glovebox AÂ Glovebox – also known as an atmospheric enclosure or an inert gas enclosure – is a sealed work area with built-in glove ports and pass-through chambers and interlocking doors to allow the introduction and manipulation of objects in a controlled working environment. Typical applications include the hermetic sealing of electronic components which requires a high purity, moisture-free inert atmosphere such as Argon, Nitrogen, Helium, or a combination of these gases.